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Journal of Indian Society of Pedodontics and Preventive Dentistry Official publication of Indian Society of Pedodontics and Preventive Dentistry
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 ORIGINAL ARTICLE
Year : 2021  |  Volume : 39  |  Issue : 3  |  Page : 279-283

A clinical trial on topical effect of probiotics on oral Streptococcus mutans counts in children


1 Department of Pediatric and Preventive Dentistry, Stes's Sinhgad Dental College and Hospital, Pune, Maharashtra, India
2 Department of Orthodontics and Dentofacial Orthopedics, Stes's Sinhgad Dental College and Hospital, Pune, Maharashtra, India

Correspondence Address:
Dr. Raju Umaji Patil
Department of Pediatric and Preventive Dentistry, Stes's Sinhgad Dental College and Hospital, S. No: 44/1 Vadgaon Bk Off. Sinhgad Road, Pune - 411 041, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jisppd.jisppd_519_20

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Background: Probiotics compete with the cariogenic oral bacteria like Streptococcus mutans (S. mutans) for carbohydrates resulting in substrate depletion and reduction in the number of S. mutans. Aim: The evaluation of topical effect of short-term application of Probiotic formulation on S. mutans counts in plaque of 7-12 years old children with decayed, missing, filled teeth (dmft/DMFT) score 2-5. Materials and Methods: A registered randomized clinical trial (Clinical Trials Registry of India/ICMR - CTRI/2019/09/021205) was conducted on 7-12 years medium risk 10 children with dmft/DMFT score 2-5, where an innovative probiotic formulation (prepared from capsule) was applied for 6 consecutive days, on teeth and pre/post plaque samples were evaluated for S. mutans count on mitis salivarius agar. Results: There was statistically significant and drastic reduction from 608,200 to 6600 (>90%) in the S. mutans count in plaque after the application of probiotic solution for a short period of time (6 days). Conclusion: Short-term application of probiotics can be used as an alternate topical preventive therapy to reduce the count of S. mutans effectively in oral cavity/plaque. Hence, probiotic can be used as topical caries preventive agent.






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  2005 - Journal of Indian Society of Pedodontics and Preventive Dentistry | Published by Wolters Kluwer - Medknow 
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