| ORIGINAL ARTICLE |
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| Year : 2017 | Volume
: 35
| Issue : 3 | Page : 229-237 |
A comparative evaluation of the remineralization potential of three commercially available remineralizing agents on white spot lesions in primary teeth: An in vitro study
Pujan Kamath1, Rashmi Nayak1, Shobha U Kamath2, Deepika Pai1
1 Department of Pedodontics and Preventive Dentistry, Manipal College of Dental Sciences Manipal, Manipal University, Manipal, Karnataka, India
2 Department of Biochemistry, KMC Manipal, Manipal University, Manipal, Karnataka, India
Correspondence Address:
Rashmi Nayak
Department of Pedodontics and Preventive Dentistry, Room No. 6, Manipal College of Dental Sciences Manipal, Manipal University, Manipal - 576 104, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/JISPPD.JISPPD_242_16
Background: The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents. Aim: This study aimed to compare and evaluate the remineralization potential of commercially available agents containing nano-hydroxyapatite (nano-HA), casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF), and Tricalcium phosphate (TCP) on artificially induced white spot lesions in primary teeth. Settings and Design: This is an in vitro double-blind randomized study. Materials and Methods: Forty extracted or exfoliated primary teeth were selected and randomized as follows: Group I: FTCP, Group II: fluoridated dentifrice, Group III: CPP-ACPF, and Group IV: Nano-HA. DIAGNOdent readings and scanning electron microscope (SEM) energy dispersive X-ray (EDX) analysis were carried out at baseline. The samples were subjected to the test agents after inducing white spot lesions. The readings were repeated postdemineralization and postremineralization. Statistical Analysis: The data were analyzed using IBM SPSS version 20 software with one-way ANOVA, post hoc Tukey's HSD, and paired t-test. Results: SEM evaluation showed favorable surface changes in all the four study groups after remineralization therapy. Intragroup comparison of DIAGNOdent and EDX readings showed a highly significant difference between baseline, postdemineralization, and postremineralization values. However, the intergroup comparison was statistically nonsignificant. Conclusion: All test agents were comparable in their remineralization potential.
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