| ORIGINAL ARTICLE |
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| Year : 2010 | Volume
: 28
| Issue : 2 | Page : 91-94 |
Natural prevalence of antibody titers to Glucostltransferase of Streptococcus mutans in serum in high and low caries active children
BC Kirtaniya1, HS Chawla2, A Tiwari3, NK Ganguly4, V Sachdev5
1 Professor, Department of Pedodontics, Himachal Dental College, Sunder Nagar, Himachal Pradesh, India
2 Former Professor and Head, Oral health science Centre, PGIMER, Chandigarh, India
3 Former Dean, PGIMER, former Professor and Head, Oral Health Science Centre, PGIMER, Chandigarh, India
4 Director, ICMR, New Delhi, former Professor and Head, Experimental Medicine, PGIMER, Chandigarh, India
5 Principal, Professor and Head, Himachal Dental College, Sunder Nagar, Himachal Pradesh, India
Correspondence Address:
B C Kirtaniya
Department of Pedodontics, Himachal Dental College, Sunder Nagar, Himachal Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0970-4388.66744
In this investigation, serum immunoglobulin G (IgG) and immunoglobulin A (IgA) titers, as well as total immunoglobulin concentration (IgG + IgA + IgM), were found to be raised with the increase in the number of dental caries. Only the total serum antibody titer in high dental caries (HDC) group was found to be significantly raised as compared to no dental carries (NDC) group. Although the IgG and IgA titers were raised in blood with the increased number of caries, the results were not statistically significant. However, we could not find any correlation between serum antibodies and dental caries except that there was an increased trend of serum antibodies to GTF with the increased number of carious lesions.
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