Home | About Us | Editorial Board | Current Issue | Archives | Search | Instructions | Subscription | Feedback | e-Alerts | Login 
Journal of Indian Society of Pedodontics and Preventive Dentistry Official publication of Indian Society of Pedodontics and Preventive Dentistry
 Users Online: 561  
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size

Year : 2008  |  Volume : 26  |  Issue : 6  |  Page : 79-81

A rare case of concomitant hypo-hyperdontia in identical twins

Department of Pedodontics, Seema Dental College and Hospital, Rishikesh-249 203, Uttarakhand, India

Correspondence Address:
A Sharma
A/17, HIHT Campus, Jolly Grant, P.O.-Doiwala 248 140, Dehradun, Uttarakhand
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 19075454

Rights and PermissionsRights and Permissions



Concomitant hypodontia and hyperdontia is a rare condition of unknown etiology. One such case of occurring in identical twins in mixed dentition is presented and discussed. A sibling, especially a twin of an affected patient, should be suspected of having a similar problem, even if he or she is asymptomatic. Genetic factors probably play an important etiological role in the co-occurence of partial anodontia and supernumerary teeth.

Keywords: Hypodontia, hyperdontia, mesiodens, tuberculate tooth

How to cite this article:
Sharma A. A rare case of concomitant hypo-hyperdontia in identical twins. J Indian Soc Pedod Prev Dent 2008;26, Suppl S2:79-81

How to cite this URL:
Sharma A. A rare case of concomitant hypo-hyperdontia in identical twins. J Indian Soc Pedod Prev Dent [serial online] 2008 [cited 2023 Feb 1];26, Suppl S2:79-81. Available from: http://www.jisppd.com/text.asp?2008/26/6/79/43538

   Introduction Top

Concomitant hypo-hyperdontia is a condition where congenital absence of teeth and an excess number of teeth are present in the same individual. It is a very rare condition, with only few case reports in the literature. [1],[2],[3],[4],[5],[6],[7],[8],[9],[10],[11] It has been found more often in the permanent dentition than in the primary or mixed dentition. [12] Though its etiology is unknown, disturbances in migration, proliferation, and differentiation of the neural crest cells and interactions between the epithelial and mesenchymal cells during the initiation of odontogenesis have been suggested as possible causes. [12],[13]

Presented here is the first such case to be reported in identical twins in mixed dentition.

   Case Report Top

A 7-year-old male, accompanied by his father reported to the department of pedodontics with the complaint of a tooth seen to be erupting since the last 3 months behind the upper front teeth and causing difficulty while speaking. A review of his family and medical histories showed nothing remarkable though it revealed that the patient had a twin brother. No abnormality was noted during the general physical /extraoral examination. Intraoral examination [Figure 1] showed a palatally erupting tuberculate mesiodens in relation to 61. Radiographic examination [Figure 2] and [Figure 3] revealed bilateral presence of two tuberculate mesiodentes, one erupted and causing rotation of 21, while the other was seen impacted in relation to 51. the maxillary left second premolar was found to be missing. The erupted mesiodens was extracted.

The patient and the parent were given a detailed explanation regarding the condition and advised follow-up every 2 months; they were also asked to bring the brother at the next visit. The father was made aware of the possibility of a similar situation in the other twin. However, it was after a year had elapsed that he visited the department with both the children, who were seen to be identical twins [Figure 4].

Now complained of the other erupting tooth hindering tongue movements, though it had become visible in the mouth 10 months back. Intraoral and radiographic examination [Figure 5] and [Figure 6] showed a palatally erupting tuberculate mesiodens in relation to 51; it was extracted along with the primary maxillary central incisors.

Dental history of the twin brother revealed that he had a maxillary midline supernumerary tooth which was erupting since the last 2 months. Clinical and radiographic examination showed a tuberculate mesiodens between the primary central incisors [Figure 7] and [Figure 8]. The mandibular left second premolar was observed to be missing [Figure 9]. The retained 51, 61, 81, and mesiodens were extracted. Both the brothers were kept on 6-monthly recall.

   Discussion Top

Human dental eruption is known to be a dynamic interaction between heredity and environment. It is widely assumed that the development of supernumerary teeth or congenitally missing teeth may involve a genetic factor and, hence, may show a familial tendency. [11],[14],[15] Monozygotic / identical twins showing discordance for expression of hypodontia or hyperdontia have also been reported. [16],[17] The co-occurrence of supernumeraries and partial anodontia in the present case suggests its genetic predisposition, as it is axiomatic that the identical twins have same genotypes. The variable expression of the concomitant condition in the twins is however notable and thus makes them a discordant pair.

Cases exhibiting absent premolars associated with a mesiodens were noted by Mercer, [5] Nathanail, [4] and Gibson. [7] But the case reported here is unusual, as tuberculate mesiodentes in relation to the primary central incisors is a rare occurrence. Supernumeraries in primary dentition are usually normal (supplemental type) or conical in shape. A tuberculate supernumerary tooth rarely erupts in childhood. [18]

During the mixed dentition years, treatment planning should be based on the dental age rather than the chronological age of the patient, hence case was kept under observation. Good quality premolars seldom form after the child is 8 years of age. [19] Early diagnosis of absence of teeth can reduce orthodontic complications and assist in treatment planning. A thorough evaluation of facial profile, incisor position, space requirements, and the status of the primary teeth is crucial to determine the correct treatment for congenitally missing permanent teeth. Early diagnosis of mesiodentes allowed an early conservative intervention and thus a more favorable prognosis.

   References Top

1.Stafne EC. Supernumerary teeth. Dent Cosmos 1932;74:653-9.  Back to cited text no. 1    
2.Camilleri GE. Concomitant hypodontia and hyperdontia: Case report. Br Dent J 1967;123:338-9.  Back to cited text no. 2  [PUBMED]  
3.Munns D. A case of partial anodontia and supernumerary tooth present in the same jaw. Dent Pract Dent Rec 1967;18:34-7.  Back to cited text no. 3  [PUBMED]  
4.Brook AH, Winter GB. Letter to Editor. Br Dent J 1970;129:195.  Back to cited text no. 4    
5.Nathanail P. Letter to Editor. Br Dent J 1970;129:309.  Back to cited text no. 5    
6.Mercer AE. Letter to Editor. Br Dent J 1970;129:402.  Back to cited text no. 6    
7.Low T. Hypodontia and supernumerary tooth: report of a case and its management. Br J Orthod 1977;4:187-90.  Back to cited text no. 7  [PUBMED]  
8.Gibson AC. Concomitant hypo-hyperdontia. Br J Orthod 1979;6:101-5.  Back to cited text no. 8  [PUBMED]  
9.Spyropoulos ND, Patsakas AJ, Angelopoulos AP. Simultaneous presence of partial anodontia and supernumerary teeth. Oral Surg Oral Med Oral Pathol 1979;48:53-6.  Back to cited text no. 9  [PUBMED]  
10.Macpherson DW. Dental anomalies in fucosidosis. Br Dent J 1991;170:408-10.  Back to cited text no. 10  [PUBMED]  
11.Zhu JF, Marcushamer M, King DL, Henry RJ. Supernumerary and congenitally absent teeth: A literature review. J Clin Pediatr Dent 1996;20:87-95.  Back to cited text no. 11    
12.Ranta R. Numeric anomalies of teeth in concomitant hypodontia and hyperdontia. J Craniofac Genet Dev Biol 1988;8:245-51.  Back to cited text no. 12  [PUBMED]  
13.Mina M, Kollar EJ. The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch Oral Biol 1987;32:123-7.  Back to cited text no. 13  [PUBMED]  
14.Developmental disturbances of oral and paraoral structures. In: Shafer WG, Hine MK, Levy BM, editors. A Text Book of Oral Pathology. 4 th ed. Philadelphia: WB Saunders Company 1993. p. 45-50.  Back to cited text no. 14    
15.Schulze C. Developmental abnormalities of the teeth and jaws. In: Gorlin RJ, Goldman HM, editors. Thoma's Oral Pathology. 6 th ed. St. Louis: The CV Mosby Co; 1970. p. 96-183.  Back to cited text no. 15    
16.Rubin MM, Nevins A, Berg M, Borden B. A comparison of identical twins in relation to three dental anomalies: Multiple supernumerary teeth, juvenile periodontosis, and zero caries incidence. Oral Surg Oral Med Oral Pathol 1981;52:391-4.  Back to cited text no. 16  [PUBMED]  
17.Kindelan JD, Rysiecki G, Childs WP. Hypodontia: Genotype or environment? A case report of monozygotic twins. Br J Orthod 1998;25:175-8.  Back to cited text no. 17    
18.Hattab FN, Yassin OM, Rawashdeh MA. Supernumerary teeth: Report of three cases and review of the literature. ASDC J Dent Child 1994;61:382-93.  Back to cited text no. 18  [PUBMED]  
19.Fields HW. Treatment of nonskeletal problems in preadolescent children. In: Proffit WR, editor. Contemporary Orthodontics. 2 nd ed. St. Louis: Mosby-Year Book, Inc; 1993. p. 403.  Back to cited text no. 19    


  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5], [Figure 6], [Figure 7], [Figure 8], [Figure 9]

This article has been cited by
1 Management of congenitally missing second premolars in a growing child
Jha, P. and Jha, M.
Journal of Conservative Dentistry. 2012; 15(2): 187-190
2 Case report: A rare occurrence of non-syndromic hypo-hyperdontia in the mandibular anterior region
Verma, K.G. and Verma, P. and Rishi, S.
European Archives of Paediatric Dentistry. 2012; 13(1): 47-49


Print this article  Email this article
Previous article Next article


   Next article
   Previous article 
   Table of Contents
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Article in PDF (167 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

    Case Report
    Article Figures

 Article Access Statistics
    PDF Downloaded473    
    Comments [Add]    
    Cited by others 2    

Recommend this journal

Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer | Privacy Notice
  2005 - Journal of Indian Society of Pedodontics and Preventive Dentistry | Published by Wolters Kluwer - Medknow 
Online since 1st May '05